Inherited Disorders

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Inherited Disorders




Inherited Disorders

Cardiovascular

Factor VIII Deficiency
Haemophilia A is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia.

Von Willebrand's disease
Von Willebrand disease (vWD)arises from a qualitative or quantitative deficiency of von Willebrand factor (vWF), a multimeric protein that is required for platelet adhesion. It is known to affect humans and dogs.

Endocrine

Hypothyroidism
Hypothyroidism is the disease state in humans and animals caused by insufficient production of thyroid hormone by the thyroid gland.

Gastrointestinal

Megaoesophagus
Megaoesophagus is characterised by the dilation of the oesophagus which then prevents food or water from passing into the stomach (causing vomiting).

Immune

Vasculopathy
Vasculopathy is a disorder that causes ulceration of the pads of the paws.

Integument

Cutaneous Asthenia
Cutaneous Asthenia is an inherited autosomal recessive connective tissue disorder. Affected animals have extremely fragile skin that tears easily and exhibits impaired healing.

Hygroma
Hygroma is a cystic tumor of lymphatic origin. The swellings are usually found on the elbows and hocks.

Musculoskeletal

Osteochondritis dissecans
Osteochondritis dissecans (sometimes spelled dessecans, and abbreviated "OCD") is a painful condition within a joint of the body in humans or animals, in which fragments of cartilage or bone have become loose within a joint, leading to pain and inflammation.

Nervous/Sensory

Anesthetic idiosyncracy
An abnormal sensitivity to anesthetic agents that can cause cardiac or respiratory arrest.

Cataract
A cataract is a clouding that develops in the crystalline lens of the eye or in its envelope, varying in degree from slight to complete opacity and obstructing the passage of light.

Corneal Dystrophy
Corneal dystrophy is a group of disorders, characterised by a noninflammatory, inherited, bilateral opacity of the transparent front part of the eye called the cornea.

Distichiasis
A distichia is an eyelash that arises from an abnormal spot on the eyelid of a dog. Distichiae usually exit from the duct of the meibomian gland at the eyelid margin.

Epilepsy
Epilepsy is a common chronic neurological disorder that is characterized by recurrent unprovoked seizures. These seizures are transient signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain.

Lens Luxation
Ectopia lentis is a displacement or malposition of the eye's crystalline lens from its normal location. A partial dislocation of a lens is termed lens subluxation or subluxated lens; a complete dislocation of a lens is termed lens luxation or luxated lens.

Optic nerve hypoplasia
Optic nerve hypoplasia is a medical condition that results in underdevelopment of the optic nerves.

Pannus
Chronic superficial keratitis (CSK), also known as pannus or Uberreiter’s disease, is an inflammatory condition of the cornea in dogs.

Persistent pupillary membrane
Persistent pupillary membrane (PPM) is a condition of the eye involving remnants of a fetal membrane that persist as strands of tissue crossing the pupil.

Progressive Retinal Atrophy (PRA) (X-linked)
PRA is characterized by the bilateral degeneration of the retina, causing progressive vision loss culminating in blindness.


Other Disorders

Atrophic Follicular Dysplasia
Characterised by bilateral hair loss on the lateral and caudal thighs.

Gastric Torsion
Bloat is a medical condition in which the stomach becomes overstretched by excessive gas content.


Written content used with permission (C) Greyhound Haven 2010 - 2016

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